Quality index of false soldering strength and barr

Analysis and detection of quality indexes of false soldering strength and barrier performance of multi chamber infusion soft bags

multi chamber (multi chamber) infusion soft bags are mainly divided into two types in the field of large infusion, one is liquid-liquid multi chamber bag, the other is powder liquid multi chamber bag; It refers to the collection of strategic emerging industries including new materials in the production process and storage There will be no during transportation "The drugs for infusion in the same key areas should be packed in the same package, separated in different chambers through virtual welding, and opened by external force during clinical use. After mixing, the multi chamber soft liquid soft bag products are mainly suitable for unstable preparation and can not be stored for a long time. In clinical medication, it is necessary to prepare infusion preparations temporarily. This paper only focuses on the two quality key factors of virtual welding performance and barrier performance of multi chamber infusion soft bag products Analysis

1. Analysis and detection of false soldering strength

for liquid-liquid multi chamber bags and powder liquid multi chamber bags, the false soldering strength must ensure the convenience and safety of clinical use and the separation efficiency of products in storage and transportation. Therefore, the control of false sealing process of multi chamber bags is a key step in the whole production process. The performance of false welding mainly depends on three parameters: temperature, time and pressure. In the use of multi compartment bag, on the one hand, in order to ensure the safety of storage and transportation, on the other hand, it should ensure the operability of clinical use, so the strength of virtual welding (or heat sealing strength) should not be too large or too small. How to control this index has become the focus of multi room infusion bag manufacturers. Labthink Languang's hst-h3 heat sealing tester and XLW (PC) intelligent electronic tensile testing machine are specialized in the detection of this index of multi chamber infusion software. When testing the finished multi chamber bag, the false welding part is directly cut to prepare the sample, and then the test can be completed automatically after selecting the heat sealing strength test item on XLW (PC). In addition, as a manufacturer of infusion products, in order to pursue the appropriate virtual welding strength, it is often necessary to study the three parameters of welding sealing temperature, time and pressure. At this time, it is necessary to analyze the best heat sealing temperature, time and pressure parameters with the help of hst-h3 heat sealing tester and intelligent electronic tensile testing machine

2. Analysis and detection of barrier performance

barrier performance is an important factor affecting the quality of multi compartment bags. Whether liquid-liquid multi compartment bags or powder liquid multi compartment bags, because the barrier of contact packaging of such products is not high, in order to ensure that the products can block the penetration of oxygen and water vapor, a layer of barrier packaging needs to be added to the inner packaging (contact packaging) to block the penetration of oxygen and water vapor. In addition, in the production process, it is necessary to use the nitrogen replacement packaging machine to replace the air between the inner bag and the barrier bag. Therefore, in the barrier test, in addition to testing the oxygen penetration (2) barrel: it is the amount of 1 metal seamless tube, it is also necessary to test the nitrogen penetration, excessive water vapor penetration and other indicators. Labthink Languang's vac-v series four differential pressure gas Penetrameters can well complete the detection of corresponding indicators

the application of multi compartment bag is a significant improvement in the function of infusion soft bag. As one of the most stringent packages in drug packaging, its testing indexes such as tensile strength and elongation, heat sealing strength, film puncture performance, rubber plug puncture force, sealing and other quality indexes also need to be tested. As an excellent provider of testing instruments and testing services, Labthink Languang has continuously provided the best and most comprehensive quality control solutions for the pharmaceutical field all over the world for many years. We hope to have more extensive exchanges and cooperation with enterprises and institutions in the pharmaceutical industry. For more information, you can call Jinan Languang directly